Pericytes modulate endothelial sprouting
نویسندگان
چکیده
منابع مشابه
Inflammation-induced endothelial cell-derived extracellular vesicles modulate the cellular status of pericytes
Emerging lines of evidence have shown that extracellular vesicles (EVs) mediate cell-to-cell communication by exporting encapsulated materials, such as microRNAs (miRNAs), to target cells. Endothelial cell-derived EVs (E-EVs) are upregulated in circulating blood in different pathological conditions; however, the characteristics and the role of these E-EVs are not yet well understood. In vitro s...
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متن کاملCo-culture of endothelial cells with pericytes results in an inhibition of the proliferation and movement of endothelial cells. Although endothelial cells promote the growth of pericytes by secretion of endothelin-1, the inhibition of endothelial cell growth of pericytes
cytes. Pericytes are elongated cells of mesodermal origin that wrap around and along endothelial cells in small vessels. Co-culture of endothelial cells with pericytes results in an inhibition of the proliferation and movement of endothelial cells. Although endothelial cells promote the growth of pericytes by secretion of endothelin-1, the inhibition of endothelial cell growth of pericytes is a...
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The cells of the retinal microvasculature consist predominantly of mesodermally derived pericytes and endothelial cells, and the regulatory factors which govern their co-ordinated growth and define their phenotypic characteristics in vivo may be regarded as key elements of the angiogenic process. An investigation of these cells in co-culture experiments has led to the identification of a potent...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2013
ISSN: 1755-3245,0008-6363
DOI: 10.1093/cvr/cvt215